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Flohsamenschalen - Wirkungen gegen Verstopfung und Durchfall

  1. A. L. Romero-Baranzini, O. G. Rodriguez, G. A. Yanez-Farias, J. M. Barron-Hoyos, P. Rayas-Duarte: Chemical, Physicochemical, and Nutritional Evaluation of Plantago (Plantago ovata Forsk); Cereal Chemistry 83(4) July/August 2006:358-362; http://dx.doi.org/10.1094/CC-83-0358
  2. Ranbir Singh Fougat, Chaitanya Joshi, Kalyani Kulkarni, Sushil Kumar, Anand Patel, Amar Sakure, Jigar Mistry: Rapid Development of Microsatellite Markers for Plantago ovata Forsk.: Using Next Generation Sequencing and Their Cross-Species Transferability; Agriculture 2014, 4(2), 199-216; doi:10.3390/agriculture4020199; Published: 20 June 2014
  3. Ranbir Singh Fougat, Chaitanya Joshi, Kalyani Kulkarni, Sushil Kumar, Anand Patel, Amar Sakure, Jigar Mistry: Rapid Development of Microsatellite Markers for Plantago ovata Forsk.: Using Next Generation Sequencing and Their Cross-Species Transferability; Agriculture 2014, 4(2), 199-216; doi:10.3390/agriculture4020199; Published: 20 June 2014
  4. Manish K. Patel, Avinash Mishra, Bhavanath Jha: Non-targeted Metabolite Profiling and Scavenging Activity Unveil the Nutraceutical Potential of Psyllium (Plantago ovata Forsk); Front Plant Sci. 2016; 7: 431.; Published online 2016 Apr 5.; doi: 10.3389/fpls.2016.00431; PMCID: PMC4821064
  5. Mounsey A, Raleigh M, Wilson A.: Management of Constipation in Older Adults.; Am Fam Physician. 2015 Sep 15;92(6):500-4.
  6. Vipin Kumar Sharma, Bhaskar Mazumder, Vinod Nautiyal: Rheological Characterization of Isabgol Husk, Gum Katira Hydrocolloids, and Their Blends; Int J Food Sci. 2014; 2014: 506591.; Published online 2014 Aug 25.; doi: 10.1155/2014/506591; PMCID: PMC4745528
  7. Webster DJ, Gough DC, Craven JL.: The use of bulk evacuant in patients with haemorrhoids.; Br J Surg. 1978 Apr;65(4):291-2.; PMID: 346140
  8. José Carlos López, Rosa Villanueva, David Martínez-Hernández, Romana Albaladejo, Enrique Regidor, and María Elisa Calle: Plantago Ovata Consumption and Colorectal Mortality in Spain, 1995–2000; J Epidemiol. 2009; 19(4): 206–211.; Published online 2009 Jul 5. Prepublished online 2009 Jun 27. doi: 10.2188/jea.JE20080059; PMCID: PMC3924111
  9. Pawar H, Varkhade C.: Isolation, characterization and investigation of Plantago ovata husk polysaccharide as superdisintegrant.; Int J Biol Macromol. 2014 Aug;69:52-8. doi: 10.1016/j.ijbiomac.2014.05.019. Epub 2014 May 19.; PMID: 24854213
  10. Edwards S, Chaplin MF, Blackwood AD, Dettmar PW.: Primary structure of arabinoxylans of ispaghula husk and wheat bran.; Proc Nutr Soc. 2003 Feb;62(1):217-22.; PMID: 12756970
  11. Manish K. Patel, Avinash Mishra, Bhavanath Jha: Non-targeted Metabolite Profiling and Scavenging Activity Unveil the Nutraceutical Potential of Psyllium (Plantago ovata Forsk); Front Plant Sci. 2016; 7: 431.; Published online 2016 Apr 5.; doi: 10.3389/fpls.2016.00431; PMCID: PMC4821064
  12. Manish K. Patel, Avinash Mishra, Bhavanath Jha: Non-targeted Metabolite Profiling and Scavenging Activity Unveil the Nutraceutical Potential of Psyllium (Plantago ovata Forsk); Front Plant Sci. 2016; 7: 431.; Published online 2016 Apr 5.; doi: 10.3389/fpls.2016.00431; PMCID: PMC4821064
  13. Manish K. Patel, Avinash Mishra, Bhavanath Jha: Non-targeted Metabolite Profiling and Scavenging Activity Unveil the Nutraceutical Potential of Psyllium (Plantago ovata Forsk); Front Plant Sci. 2016; 7: 431.; Published online 2016 Apr 5.; doi: 10.3389/fpls.2016.00431; PMCID: PMC4821064
  14. Shivanjali Kotwal, Sanjana Kaul, Pooja Sharma, Mehak Gupta, Rama Shankar, Mukesh Jain, Manoj K. Dhar: De Novo Transcriptome Analysis of Medicinally Important Plantago ovata Using RNA-Seq; PLoS One. 2016; 11(3): e0150273.; Published online 2016 Mar 4.; doi: 10.1371/journal.pone.0150273; PMCID: PMC4778938
  15. University of Maryland Medical Center (UMMC): Constipation; abgerufen am 28.08.2016
  16. Ashwini R. Madgulkar, Monica R. P. Rao , Deepa Warrier: Characterization of Psyllium (Plantago ovata) Polysaccharide and Its Uses; Polysaccharides pp 871-890; Date: 05 June 2015
  17. Davies GJ, Dettmar PW, Hoare RC.: The influence of ispaghula husk on bowel habit.; J R Soc Promot Health. 1998 Oct;118(5):267-71.; PMID: 10076686
  18. Dettmar PW, Sykes J.: A multi-centre, general practice comparison of ispaghula husk with lactulose and other laxatives in the treatment of simple constipation.; Curr Med Res Opin. 1998;14(4):227-33.; PMID: 9891195; DOI: 10.1185/03007999809113363
  19. Judith A Marlett, Theresa M Kajs, Milton H Fischer: An unfermented gel component of psyllium seed husk promotes laxation as a lubricant in humans; Am J Clin Nutr September 2000 vol. 72 no. 3 784-789
  20. ASHRAF, W., PARK, F., LOF, J., QUIGLEY, E. M. M. (1995): Effects of psyllium therapy on stool characteristics, colon transit and anorectal function in chronic idiopathic constipation. Alimentary Pharmacology & Therapeutics, 9: 639–647. doi:10.1111/j.1365-2036.1995.tb00433.x
  21. Judith A Marlett, Theresa M Kajs, Milton H Fischer: An unfermented gel component of psyllium seed husk promotes laxation as a lubricant in humans; Am J Clin Nutr September 2000 vol. 72 no. 3 784-789
  22. Judith A Marlett, Theresa M Kajs, Milton H Fischer: An unfermented gel component of psyllium seed husk promotes laxation as a lubricant in humans; Am J Clin Nutr September 2000 vol. 72 no. 3 784-789
  23. P Marteau, B Flourié, C Cherbut, J L Corrèze, P Pellier, J Seylaz, J C Rambaud: Digestibility and bulking effect of ispaghula husks in healthy humans.; Gut 1994;35:1747-1752; doi:10.1136/gut.35.12.1747
  24. H L Chen, V S Haack, C W Janecky, N W Vollendorf, J A Marlett: Mechanisms by which wheat bran and oat bran increase stool weight in humans.; Am J Clin Nutr September 1998 vol. 68 no. 3 711-719
  25. McRorie JW, Daggy BP, Morel JG, Diersing PS, Miner PB, Robinson M.: Psyllium is superior to docusate sodium for treatment of chronic constipation.; Aliment Pharmacol Ther. 1998 May;12(5):491-7.; PMID: 9663731
  26. Manish K. Patel, Avinash Mishra, Bhavanath Jha: Non-targeted Metabolite Profiling and Scavenging Activity Unveil the Nutraceutical Potential of Psyllium (Plantago ovata Forsk); Front Plant Sci. 2016; 7: 431.; Published online 2016 Apr 5.; doi: 10.3389/fpls.2016.00431; PMCID: PMC4821064
  27. Manish K. Patel, Avinash Mishra, Bhavanath Jha: Non-targeted Metabolite Profiling and Scavenging Activity Unveil the Nutraceutical Potential of Psyllium (Plantago ovata Forsk); Front Plant Sci. 2016; 7: 431.; Published online 2016 Apr 5.; doi: 10.3389/fpls.2016.00431; PMCID: PMC4821064
  28. Manish K. Patel, Avinash Mishra, Bhavanath Jha: Non-targeted Metabolite Profiling and Scavenging Activity Unveil the Nutraceutical Potential of Psyllium (Plantago ovata Forsk); Front Plant Sci. 2016; 7: 431.; Published online 2016 Apr 5.; doi: 10.3389/fpls.2016.00431; PMCID: PMC4821064
  29. Güçlü-Ustündağ O, Mazza G.: Saponins: properties, applications and processing.; Crit Rev Food Sci Nutr. 2007;47(3):231-58.; PMID: 17453922; DOI: 10.1080/10408390600698197
  30. Chaplin MF, Chaudhury S, Dettmar PW, Sykes J, Shaw AD, Davies GJ.: Effect of ispaghula husk on the faecal output of bile acids in healthy volunteers.; J Steroid Biochem Mol Biol. 2000 Apr;72(5):283-92.; PMID: 10822018
  31. José Carlos López, Rosa Villanueva, David Martínez-Hernández, Romana Albaladejo, Enrique Regidor, and María Elisa Calle: Plantago Ovata Consumption and Colorectal Mortality in Spain, 1995–2000; J Epidemiol. 2009; 19(4): 206–211.; Published online 2009 Jul 5. Prepublished online 2009 Jun 27. doi: 10.2188/jea.JE20080059; PMCID: PMC3924111
  32. Sohn VR, Giros A, Xicola RM, Fluvià L, Grzybowski M, Anguera A, Llor X.: Stool-fermented Plantago ovata husk induces apoptosis in colorectal cancer cells independently of molecular phenotype.;Br J Nutr. 2012 Jun;107(11):1591-602. doi: 10.1017/S0007114511004910. Epub 2011 Sep 29.; PMID: 22018732
  33. Bonithon-Kopp, Claire et al.: Calcium and fibre supplementation in prevention of colorectal adenoma recurrence: a randomised intervention trial; The Lancet Volume 356, Issue 9238, 1300 - 1306
  34. Belknap D, Davidson LJ, Smith CR.: The effects of psyllium hydrophilic mucilloid on diarrhea in enterally fed patients.; Heart Lung. 1997 May-Jun;26(3):229-37.; PMID: 9176691
  35. Washington N, Harris M, Mussellwhite A, Spiller RC.: Moderation of lactulose-induced diarrhea by psyllium: effects on motility and fermentation.; Am J Clin Nutr. 1998 Feb;67(2):317-21.; PMID: 9459381
  36. Ranbir Singh Fougat, Chaitanya Joshi, Kalyani Kulkarni, Sushil Kumar, Anand Patel, Amar Sakure, Jigar Mistry: Rapid Development of Microsatellite Markers for Plantago ovata Forsk.: Using Next Generation Sequencing and Their Cross-Species Transferability; Agriculture 2014, 4(2), 199-216; doi:10.3390/agriculture4020199; Published: 20 June 2014
  37. Washington N, Harris M, Mussellwhite A, Spiller RC.: Moderation of lactulose-induced diarrhea by psyllium: effects on motility and fermentation.; Am J Clin Nutr. 1998 Feb;67(2):317-21.; PMID: 9459381
  38. MacMahon M, Carless J.: Ispaghula husk in the treatment of hypercholesterolaemia: a double-blind controlled study.; J Cardiovasc Risk. 1998 Jun;5(3):167-72.; PMID: 10201553
  39. James W Anderson, Lisa D Allgood, Jan Turner, Peter R Oeltgen, Bruce P Daggy: Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia; Am J Clin Nutr October 1999 vol. 70 no. 4 466-473
  40. Kawatra, Asha et al.: Hypocholesterolemic effect of isabgol husk in overweight adults; Nutrition Research Volume 10, Issue 10, 1177 - 1182
  41. Anna Crescenti, Rosa Solà, Rosa M. Valls, Anna Anguera, and Lluís Arola: Polymorphisms in LEP and NPY genes modify the response to soluble fibre Plantago ovata husk intake on cardiovascular risk biomarkers; Genes Nutr. 2013 Jan; 8(1): 127–136.; Published online 2012 Jun 6.; doi: 10.1007/s12263-012-0303-9; PMCID: PMC3534999
  42. Oliver SD.: The long-term safety and tolerability of ispaghula husk.; Perspectives in Public Health June 2000 vol. 120 no. 2 107-111; doi: 10.1177/146642400012000208
  43. Anderson JW, Allgood LD, Lawrence A, Altringer LA, Jerdack GR, Hengehold DA, Morel JG.: Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials.; Am J Clin Nutr. 2000 Feb;71(2):472-9.; PMID: 10648260
  44. Ganji V, Kies CV.: Psyllium husk fiber supplementation to the diets rich in soybean or coconut oil: hypocholesterolemic effect in healthy humans.; Int J Food Sci Nutr. 1996 Mar;47(2):103-10.; PMID: 8833174
  45. James W Anderson, Michael H Davidson, Lawrence Blonde, W Virgil Brown, W James Howard, Henry Ginsberg, Lisa D Allgood, and Kurt W Weingand: Long-term cholesterol-lowering effects of psyllium as an adjunct to diet therapy in the treatment of hypercholesterolemia; Am J Clin Nutr June 2000 vol. 71 no. 6 1433-1438
  46. Anderson JW, Allgood LD, Turner J, Oeltgen PR, Daggy BP.: Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia.; Am J Clin Nutr. 1999 Oct;70(4):466-73.; PMID: 10500014
  47. Davidson MH, Maki KC, Kong JC, Dugan LD, Torri SA, Hall HA, Drennan KB, Anderson SM, Fulgoni VL, Saldanha LG, Olson BH.: Long-term effects of consuming foods containing psyllium seed husk on serum lipids in subjects with hypercholesterolemia.; Am J Clin Nutr. 1998 Mar;67(3):367-76.; PMID: 9497178
  48. de Bock M, Derraik JG, Brennan CM, Biggs JB, Smith GC, Cameron-Smith D, Wall CR, Cutfield WS.: Psyllium supplementation in adolescents improves fat distribution & lipid profile: a randomized, participant-blinded, placebo-controlled, crossover trial.; PLoS One. 2012;7(7):e41735. doi: 10.1371/journal.pone.0041735. Epub 2012 Jul 27.; PMID: 22848584; PMCID: PMC3407232
  49. Moreno LA, Tresaco B, Bueno G, Fleta J, Rodríguez G, Garagorri JM, Bueno M.: Psyllium fibre and the metabolic control of obese children and adolescents.; J Physiol Biochem. 2003 Sep;59(3):235-42.; PMID: 15000455
  50. Anderson JW, Zettwoch N, Feldman T, Tietyen-Clark J, Oeltgen P, Bishop CW.: Cholesterol-lowering effects of psyllium hydrophilic mucilloid for hypercholesterolemic men.; Arch Intern Med. 1988 Feb;148(2):292-6.; PMID: 3277558
  51. Rodríguez-Morán M, Guerrero-Romero F, Lazcano-Burciaga G.: Lipid- and glucose-lowering efficacy of Plantago Psyllium in type II diabetes.; J Diabetes Complications. 1998 Sep-Oct;12(5):273-8.; PMID: 9747644
  52. Solà R, Bruckert E, Valls RM, Narejos S, Luque X, Castro-Cabezas M, Doménech G, Torres F, Heras M, Farrés X, Vaquer JV, Martínez JM, Almaraz MC, Anguera A.: Soluble fibre (Plantago ovata husk) reduces plasma low-density lipoprotein (LDL) cholesterol, triglycerides, insulin, oxidised LDL and systolic blood pressure in hypercholesterolaemic patients: A randomised trial.; Atherosclerosis. 2010 Aug;211(2):630-7. doi: 10.1016/j.atherosclerosis.2010.03.010. Epub 2010 Mar 17.; PMID: 20413122
  53. Anderson JW, Allgood LD, Lawrence A, Altringer LA, Jerdack GR, Hengehold DA, Morel JG.: Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials.; Am J Clin Nutr. 2000 Feb;71(2):472-9.; PMID: 10648260
  54. Sierra M, García JJ, Fernández N, Diez MJ, Calle AP.: Therapeutic effects of psyllium in type 2 diabetic patients.; Eur J Clin Nutr. 2002 Sep;56(9):830-42.; PMID: 12209371; DOI: 10.1038/sj.ejcn.1601398
  55. de Bock M, Derraik JG, Brennan CM, Biggs JB, Smith GC, Cameron-Smith D, Wall CR, Cutfield WS.: Psyllium supplementation in adolescents improves fat distribution & lipid profile: a randomized, participant-blinded, placebo-controlled, crossover trial.; PLoS One. 2012;7(7):e41735. doi: 10.1371/journal.pone.0041735. Epub 2012 Jul 27.; PMID: 22848584; PMCID: PMC3407232
  56. Pal S, Khossousi A, Binns C, Dhaliwal S, Ellis V.: The effect of a fibre supplement compared to a healthy diet on body composition, lipids, glucose, insulin and other metabolic syndrome risk factors in overweight and obese individuals.; Br J Nutr. 2011 Jan;105(1):90-100. doi: 10.1017/S0007114510003132. Epub 2010 Aug 23.; PMID: 20727237
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  58. Deters AM, Schröder KR, Smiatek T, Hensel A.: Ispaghula (Plantago ovata) seed husk polysaccharides promote proliferation of human epithelial cells (skin keratinocytes and fibroblasts) via enhanced growth factor receptors and energy production.; Planta Med. 2005 Jan;71(1):33-9.; PMID: 15678371; DOI: 10.1055/s-2005-837748
  59. Kawatra, Asha et al.: Hypocholesterolemic effect of isabgol husk in overweight adults; Nutrition Research Volume 10, Issue 10, 1177 - 1182
  60. Rodríguez-Morán M, Guerrero-Romero F, Lazcano-Burciaga G.: Lipid- and glucose-lowering efficacy of Plantago Psyllium in type II diabetes.; J Diabetes Complications. 1998 Sep-Oct;12(5):273-8.; PMID: 9747644
  61. Sierra M, Garcia JJ, Fernández N, Diez MJ, Calle AP, Sahagún AM; Farmafibra Group.: Effects of ispaghula husk and guar gum on postprandial glucose and insulin concentrations in healthy subjects.; Eur J Clin Nutr. 2001 Apr;55(4):235-43.; PMID: 11360127; DOI: 10.1038/sj.ejcn.1601147
  62. James W Anderson, Lisa D Allgood, Jan Turner, Peter R Oeltgen, Bruce P Daggy: Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia; Am J Clin Nutr October 1999 vol. 70 no. 4 466-473
  63. Sierra M, García JJ, Fernández N, Diez MJ, Calle AP.: Therapeutic effects of psyllium in type 2 diabetic patients.; Eur J Clin Nutr. 2002 Sep;56(9):830-42.; PMID: 12209371; DOI: 10.1038/sj.ejcn.1601398
  64. Seyed Ali Ziai, Bagher Larijani, Shahin Akhoondzadeh, Hossein Fakhrzadeh, Arezoo Dastpak, Fatemeh Bandarian, Afsaneh Rezai, Hassanali Naghdi Badi, Tara Emami: Psyllium decreased serum glucose and glycosylated hemoglobin significantly in diabetic outpatients; Journal of Ethnopharmacology Volume 102, Issue 2, 14 November 2005, Pages 202–207; http://dx.doi.org/10.1016/j.jep.2005.06.042
  65. Anderson JW, Allgood LD, Turner J, Oeltgen PR, Daggy BP.: Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia.; Am J Clin Nutr. 1999 Oct;70(4):466-73.; PMID: 10500014
  66. Cicero AF, Derosa G, Manca M, Bove M, Borghi C, Gaddi AV.: Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial.; Clin Exp Hypertens. 2007 Aug;29(6):383-94.; PMID: 17729055; DOI: 10.1080/10641960701578378
  67. M Nelida Fernandez-Martinez, Luis Hernandez-Echevarria, Matilde Sierra-Vega, M Jose Diez-Liebana, Angela Calle-Pardo, Demetrio Carriedo-Ule, Ana M Sahagún-Prieto, Anna Anguera-Vila, Juan Jose Garcia-Vieitez: A randomised clinical trial to evaluate the effects of Plantago ovata husk in Parkinson patients: changes in levodopa pharmacokinetics and biochemical parameters; BMC Complement Altern Med. 2014; 14: 296.; Published online 2014 Aug 12. doi: 10.1186/1472-6882-14-296; PMCID: PMC4139609
  68. McRorie JW, Daggy BP, Morel JG, Diersing PS, Miner PB, Robinson M.: Psyllium is superior to docusate sodium for treatment of chronic constipation.; Aliment Pharmacol Ther. 1998 May;12(5):491-7.; PMID: 9663731
  69. Gonlachanvit S, Coleski R, Owyang C, Hasler W.: Inhibitory actions of a high fibre diet on intestinal gas transit in healthy volunteers.; Gut. 2004 Nov;53(11):1577-82.; PMID: 15479674; PMCID: PMC1774297; DOI: 10.1136/gut.2004.041632
  70. Gonlachanvit S, Coleski R, Owyang C, Hasler W.: Inhibitory actions of a high fibre diet on intestinal gas transit in healthy volunteers.; Gut. 2004 Nov;53(11):1577-82.; PMID: 15479674; PMCID: PMC1774297; DOI: 10.1136/gut.2004.041632
  71. Oliver SD.: The long-term safety and tolerability of ispaghula husk.; Perspectives in Public Health June 2000 vol. 120 no. 2 107-111; doi: 10.1177/146642400012000208
  72. Code of Federal Regulations Title 21, Volume 4; Revised as of April 1, 2015; CITE: 21CFR201.319
  73. Vipin Kumar Sharma, Bhaskar Mazumder, Vinod Nautiyal: Rheological Characterization of Isabgol Husk, Gum Katira Hydrocolloids, and Their Blends; Int J Food Sci. 2014; 2014: 506591.; Published online 2014 Aug 25.; doi: 10.1155/2014/506591; PMCID: PMC4745528
  74. Shivanjali Kotwal, Sanjana Kaul, Pooja Sharma, Mehak Gupta, Rama Shankar, Mukesh Jain, Manoj K. Dhar: De Novo Transcriptome Analysis of Medicinally Important Plantago ovata Using RNA-Seq; PLoS One. 2016; 11(3): e0150273.; Published online 2016 Mar 4.; doi: 10.1371/journal.pone.0150273; PMCID: PMC4778938